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Bei Morbus Crohn handelt es sich um eine schwer wiegende Erkrankung. Psoriasis besiegt gibt es keine bestimmten Speisen, die Morbus Crohn nachweislich zur Abheilung bringen. Milchprodukte bei einer Laktose-Intoleranz. Prinzipiell ist Morbus Crohn kein Hindernis, Kinder zu bekommen. Eine Schwangerschaft sollte allerdings in einer Psoriasis besiegt der Please click for source geplant werden.
Bei leichteren Verlaufsformen ist keine Bettruhe angezeigt. Auch auf den Krankheitsverlauf eines bestehenden Morbus Crohn wirkt sich Tabak-Konsum negativ aus. Bleiben Sie informiert mit dem Newsletter von netdoktor. Matthias Thalhammer Medizinisches Review: FH Silvia Hecher, MSc. Allgemeine und spezielle Pathologie. Der Inhalt von netdoktor. The documents contained in this web site are presented for information purposes only.
The material is in no way intended to replace Psoriasis besiegt medical care or attention by a qualified practitioner. The materials in this web site cannot and should not be used as a basis for diagnosis or choice of treatment. Teilen Twittern Teilen Senden Drucken. Herbert Tilg Innere Medizin. Marcus Franz, Psoriasis besiegt Dr.
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Psoriasis is a long-lasting autoimmune disease which is characterized by patches of abnormal skin. They may vary in severity from small and localized to complete Psoriasis besiegt coverage. There are five main types Psoriasis besiegt psoriasis: It typically presents with red patches with white scales on top. Psoriasis besiegt of the body most commonly affected are the back of the forearms, shins, around the navel, and the scalp.
Fingernails and toenails are affected in most people Psoriasis besiegt some point in time. This may include pits in the nails or changes in nail color. Psoriasis is generally thought to be a genetic disease which is triggered by environmental factors. Symptoms often worsen during winter and with certain medications such as beta blockers or NSAIDs.
The underlying mechanism involves the immune system reacting to skin cells. Diagnosis is typically based on the signs and symptoms. There is no cure for psoriasis. However, various Psoriasis besiegt can help control the symptoms.
These areas are called plaques and are most commonly found on the elbows, Psoriasis besiegt, scalp, and back. Psoriasis besiegt may be accompanied by severe itching, swelling, and pain. It is often the result of an exacerbation of unstable plaque psoriasis, particularly following the abrupt withdrawal of systemic glucocorticoids. They include pustular, inverse, napkin, guttate, oral, and seborrheic-like forms. Pustular psoriasis appears as raised bumps filled with noninfectious pus pustules.
Psoriasis besiegt psoriasis also known as flexural psoriasis appears as Psoriasis besiegt, inflamed patches of skin. The patches frequently affect skin foldsparticularly around the genitals between the thigh and grointhe armpitsin the skin folds of an overweight abdomen known as panniculus Psoriasis besiegt, between the buttocks in the intergluteal cleft, and under the breasts in the inframammary fold. Heat, trauma, and infection are Psoriasis besiegt to play a role in the development of this atypical form of psoriasis.
Napkin psoriasis is a subtype of psoriasis common in infants Psoriasis besiegt by red papules with silver scale in the diaper area that may extend to the torso or limbs.
Guttate psoriasis is characterized by numerous small, scaly, red or pink, droplet-like lesions papules. These numerous spots of psoriasis appear over large areas of the body, primarily the trunk, but also the limbs and scalp. Guttate psoriasis is often triggered by a streptococcal infection, typically streptococcal pharyngitis.
Psoriasis in the mouth is very learn more here,  in contrast to lichen planusanother common papulosquamous disorder that commonly involves both the skin and mouth. When psoriasis involves the oral mucosa the lining of the mouthit may be asymptomatic,  but it may appear as white or grey-yellow plaques. The microscopic appearance of oral mucosa affected by geographic tongue migratory stomatitis is very similar to the appearance of psoriasis.
Seborrheic-like psoriasis is a common form of psoriasis with clinical aspects of psoriasis and seborrheic dermatitisand may be difficult to distinguish from the latter.
This form of psoriasis typically manifests as red plaques with greasy scales in areas of higher sebum production such as the scalpforeheadskin folds next to the noseskin surrounding the mouth, skin on the chest above the sternumand in skin folds. Psoriatic arthritis is a form of chronic inflammatory arthritis Psoriasis besiegt has a highly variable clinical Psoriasis besiegt and frequently occurs in association with Psoriasis besiegt and nail psoriasis.
Psoriasis besiegt can result in a sausage-shaped swelling of the fingers and toes known as dactylitis. Psoriasis can affect the nails and produces a variety of changes in the appearance of finger and toe nails. In addition to the appearance and distribution of the Psoriasis besiegt, specific medical signs may Psoriasis besiegt used by medical practitioners to assist with diagnosis. Around one-third of people with psoriasis report a family history of the disease, and researchers have identified genetic loci associated with the condition.
These findings suggest both Psoriasis besiegt genetic susceptibility and Psoriasis besiegt environmental response in developing psoriasis. Psoriasis has a strong hereditary Psoriasis besiegt, and many genes are associated with it, but it is unclear how those Psoriasis besiegt work together. Most of the identified genes relate to the immune system, particularly the major histocompatibility complex MHC and T cells.
Genetic studies are valuable due to their ability to identify molecular mechanisms and pathways for further study and potential drug targets. Classic genome-wide linkage analysis has identified nine loci on different chromosomes associated with psoriasis. They are called psoriasis Psoriasis besiegt 1 through 9 PSORS1 through PSORS9.
Within those loci are genes on pathways that lead to Psoriasis besiegt. Certain article source mutations of those genes are commonly found in psoriasis.
Some of these genes express inflammatory signal proteins, which affect cells in the immune system that are also involved in psoriasis. Some of these genes are also involved in other autoimmune diseases.
PSORS1 is located on chromosome 6 in the major histocompatibility complex MHCwhich controls important immune functions.
Three genes in the PSORS1 locus have a Psoriasis besiegt association with psoriasis vulgaris: HLA-C variant Psoriasis besiegt which encodes a Psoriasis-Symptome von Hand-Fuß class I protein; CCHCR1Psoriasis besiegt WWC, which encodes a coiled protein that is overexpressed in psoriatic epidermis; and CDSNvariant allele 5, which Psoriasis besiegt corneodesmosina protein which is expressed in the granular and cornified layers of the epidermis and upregulated in psoriasis.
Two major immune system genes under investigation are interleukin subunit beta IL12B on chromosome 5qwhich expresses interleukinB; and IL23R on chromosome 1p, which expresses the interleukin receptor, and is involved in T cell differentiation.
Interleukin receptor Psoriasis besiegt Juckende Haut. Behandlung von Pruritus have Psoriasis besiegt been strongly linked with psoriasis.
A rare mutation in the gene encoding for the CARD14 protein plus an environmental trigger was enough to cause plaque psoriasis the most common form of psoriasis. Conditions reported as worsening the disease include chronic infections, stress, and changes in season and climate. The rate of psoriasis in HIV-positive individuals is comparable to that of HIV-negative individuals, however, psoriasis tends to be more severe in people infected with HIV.
Psoriasis has been described as occurring after strep throatPsoriasis besiegt may be Psoriasis besiegt by skin source gut colonization with Staphylococcus aureus Psoriasis besiegt, Malasseziaand Candida albicans. Drug-induced Psoriasis besiegt may occur with beta blockers lithium antimalarial medications non-steroidal anti-inflammatory drugs terbinafinecalcium channel blockerscaptoprilglyburidegranulocyte colony-stimulating factor interleukinsinterferons lipid-lowering drugs: Psoriasis is characterized by an abnormally excessive and rapid growth of the epidermal layer of the skin.
Dendritic cells bridge the innate immune system and adaptive immune system. They are increased in psoriatic lesions  and induce the proliferation of T cells and type Psoriasis besiegt helper T cells Th1.
A diagnosis of psoriasis Psoriasis besiegt usually based on the appearance of the skin. Skin characteristics typical for psoriasis are scaly, erythematous plaques, papules, or patches of skin that may be painful and itch. If the clinical diagnosis is uncertain, a skin biopsy or scraping may be performed to rule out other disorders and to confirm the diagnosis. Skin from a biopsy will show clubbed epidermal projections that interdigitate with dermis on microscopy.
Epidermal thickening is another characteristic histologic finding of psoriasis lesions. Unlike their mature counterparts, these superficial cells keep their nucleus. Psoriasis is classified as a papulosquamous disorder and is most commonly subdivided into different categories based Psoriasis besiegt histological characteristics.
Each form has a dedicated ICD code. Another classification scheme considers genetic and demographic factors. Type 1 has a positive family history, starts before the age of 40, and is associated with the human leukocyte antigenHLA-Cw6.
Conversely, type 2 does not show a family history, presents after age 40, and is not http://outdoor-frauen.de/baeder-fuer-psoriasis-zalmanov.php with HLA-Cw6. The classification of psoriasis as an autoimmune disease has sparked considerable debate. Researchers have proposed differing descriptions of psoriasis and psoriatic arthritis; some authors have classified them Psoriasis besiegt autoimmune diseases    while others have classified them as distinct from autoimmune diseases and referred to them as immune-mediated inflammatory diseases.
There is no consensus about how to classify the severity of psoriasis. The DLQI score ranges from 0 minimal impairment to 30 maximal impairment Psoriasis besiegt is calculated with each answer being assigned 0—3 points with higher scores Psoriasis besiegt greater social or Psoriasis besiegt impairment.
The psoriasis area severity index PASI is the most widely used measurement tool for psoriasis. PASI assesses the Psoriasis besiegt of lesions and the area affected Psoriasis besiegt combines these two factors into a single score from 0 no disease to 72 maximal disease.
While no cure is available for psoriasis,  many treatment options exist. Psoriasis besiegt agents are typically used for mild disease, phototherapy for moderate disease, and systemic agents for Psoriasis besiegt disease.
Topical corticosteroid preparations are the most effective agents when used continuously for 8 Psoriasis besiegt retinoids and coal tar were found to be of limited benefit and may be no better than Psoriasis besiegt. Vitamin D analogues such as paricalcitol were Psoriasis besiegt to be significantly superior to placebo.
Combination therapy with Psoriasis besiegt D and a corticosteroid was superior to either treatment alone and vitamin D was found to be superior to coal tar Psoriasis besiegt chronic plaque psoriasis.
Moisturizers and emollients Psoriasis besiegt as mineral oilpetroleum jellycalcipotrioland decubal an oil-in-water emollient were found to increase the clearance of psoriatic plaques. Emollients have been shown to be even more effective at clearing psoriatic plaques when combined with phototherapy.
The emollient salicylic acid is structurally similar to para-aminobenzoic acid PABAcommonly found in sunscreen, and is known to interfere with phototherapy in psoriasis.
Coconut oilwhen used as Psoriasis besiegt emollient in psoriasis, has been found to decrease Psoriasis besiegt clearance with phototherapy. Ointment and creams containing coal tardithranolcorticosteroids i. The use of the finger tip unit may be helpful in guiding how much topical treatment to use.
Vitamin D analogues may be useful with steroids; however, alone have a higher rate of side effects. Another topical therapy used Psoriasis besiegt treat psoriasis is a form of balneotherapywhich involves daily baths in the Dead Sea. This is usually done for four weeks with the benefit attributed to sun exposure and specifically UVB light. This is cost-effective and it has been propagated as an effective way to treat psoriasis without medication.
Phototherapy in the form of sunlight has long been used for psoriasis. The UVB lamps should have a timer that will turn off the lamp when the time ends. One of Psoriasis besiegt problems with clinical phototherapy is the difficulty many patients have gaining access to a facility.
Indoor tanning resources are almost ubiquitous today and could be considered as a means for patients to get UV exposure when dermatologist provided phototherapy is not available. However, a concern with the use of commercial tanning is that tanning beds that primarily emit UVA might not effectively treat psoriasis. Psoriasis besiegt study found that plaque psoriasis is responsive to erythemogenic doses of either UVA or UVB, as exposure to either can cause dissipation of psoriatic plaques.
It does require more energy to reach erythemogenic dosing with UVA. UV light therapies all have risks; tanning beds are no exception, particularly in the link between UV light and the increased chance of skin cancer. There are increased risks of melanoma, squamous cell and basal cell carcinomas; younger psoriasis Psoriasis besiegt, particularly those under age 35, are at increased risk from melanoma see more UV light treatment.
The World Health Organization WHO listed tanning beds as carcinogens. A review of studies recommends that people Psoriasis besiegt are susceptible to skin cancers exercise caution when using UV light therapy as a treatment. A major mechanism of NBUVB is the induction of DNA damage in the form of pyrimidine dimers.
This type of phototherapy is useful in the treatment of psoriasis because the formation of these dimers this web page with the cell cycle and stops it. The interruption of the cell cycle induced by NBUVB opposes the characteristic rapid division of skin cells seen in psoriasis.
The most common short-term side effect of this form of phototherapy is redness of the skin; less common side effects of NBUVB phototherapy are itching and blistering of the treated skin, irritation of the eyes in the form of conjunctival inflammation or inflammation of the corneaor cold sores due to reactivation of the herpes simplex virus in the skin surrounding the lips. Eye protection is usually given during phototherapy treatments. Psoralen and ultraviolet A phototherapy PUVA combines the oral or topical administration of Psoriasis besiegt with exposure Psoriasis besiegt ultraviolet A UVA light.
The mechanism of action of PUVA is unknown, but probably involves activation of psoralen by UVA light, which inhibits the abnormally rapid production of the cells in psoriatic skin. PUVA is associated with nauseaheadachefatigueburning, and itching. Long-term treatment is associated with squamous cell carcinoma but not with melanoma. Psoriasis resistant Psoriasis besiegt topical treatment and phototherapy may be treated with systemic therapies including medications by mouth or injectable treatments.
The majority of people experience a recurrence of psoriasis after systemic treatment is Psoriasis besiegt. Non-biologic systemic treatments frequently used for psoriasis include methotrexateciclosporinhydroxycarbamidefumarates such as dimethyl fumarateand retinoids. These Psoriasis besiegt are also regarded as first-line treatments for psoriatic erythroderma. Biologics Psoriasis besiegt manufactured proteins that interrupt the immune process involved in psoriasis. Unlike generalised immunosuppressive drug therapies such as methotrexate, biologics target specific aspects of the immune system contributing to psoriasis.
European guidelines recommend avoiding biologics if a pregnancy is planned; anti-TNF therapies such as infliximab are not recommended for use in chronic carriers of the hepatitis B virus or individuals infected with HIV. Several monoclonal antibodies target cytokines, the molecules that cells use to send inflammatory signals to each other.
Two drugs that target T cells are efalizumab and alefacept. Efalizumab is a monoclonal antibody that specifically Psoriasis besiegt the CD11a subunit Psoriasis besiegt LFA Individuals with psoriasis may click here neutralizing antibodies against monoclonal antibodies.
Neutralization occurs when click the following article antidrug antibody Psoriasis besiegt a monoclonal antibody such as infliximab from binding antigen in a laboratory test. When infliximab no longer binds tumor necrosis factor alphait no Psoriasis besiegt decreases inflammation, and psoriasis may worsen.
Limited evidence suggests Psoriasis besiegt of the tonsils may benefit people with chronic plaque psoriasis, guttate psoriasis, and palmoplantar pustulosis.
Uncontrolled studies have suggested that individuals with psoriasis or psoriatic Psoriasis besiegt may benefit from a diet supplemented with fish oil rich in eicosapentaenoic acid EPA and docosahexaenoic acid DHA. The Psoriasis besiegt of consumption of caffeine including coffee, black tea, mate, and dark chocolate remains to be determined.
There is a higher rate of celiac disease among people Psoriasis besiegt psoriasis. Most people with psoriasis experience nothing more than mild skin lesions that can be treated effectively with topical therapies. Itching and pain can Psoriasis besiegt with basic functions, Psoriasis Risikogruppe as Psoriasis besiegt and sleep.
Individuals with psoriasis may feel self-conscious about their appearance and have a poor self-image that stems from fear of public rejection and psychosexual concerns. Psoriasis has been associated with low self-esteem and depression Psoriasis besiegt more common among those with the condition. Clinical research has indicated individuals often experience a diminished quality of life. Several conditions are associated with psoriasis.
These occur more frequently in older people. Nearly half of individuals with psoriasis over the age of 65 have at least three comorbidities, and two-thirds have at least two comorbidities. Psoriasis has been associated with obesity  and several other cardiovascular and metabolic disturbances.
Cardiovascular disease risk Psoriasis besiegt to be correlated with the severity of psoriasis and its duration. There is no strong evidence to suggest that psoriasis is associated with an increased risk of death from cardiovascular events.
Methotrexate may provide a Psoriasis besiegt of protection for the heart. The odds of having hypertension are 1. A similar association was noted in people who have psoriatic arthritis—the odds of having hypertension were found to be 2. The link between psoriasis and hypertension is not currently understood. Mechanisms hypothesized to be involved in this relationship include the following: Approximately one third of people with psoriasis report being diagnosed before age Psoriasis affects about 6.
Scholars believe psoriasis to have been included among the various skin conditions called tzaraath translated as leprosy in the Hebrew Biblea condition imposed as a punishment for slander. The patient was deemed "impure" see tumah and taharah during their afflicted phase and is ultimately treated by the kohen. They used the term psora to describe itchy skin conditions. Leprosythey said, is distinguished by the regular, circular form of Psoriasis besiegt, while Psoriasis besiegt is always irregular.
Willan identified two categories: Psoriasis is thought to have first been described in Ancient Rome by Cornelius Celsus. The disease was first classified by English physician Thomas Willan.
The British dermatologist Thomas Bateman described a possible link between psoriasis and arthritic symptoms in The Psoriasis besiegt of psoriasis is littered with treatments of dubious effectiveness and high toxicity. The International Federation of Psoriasis Associations IFPA is the global umbrella organization for national and regional psoriasis patient associations and also gathers Psoriasis besiegt leading experts in psoriasis and psoriatic arthritis research for scientific Psoriasis besiegt every three years.
Non-profit organizations the National Psoriasis Foundation in the United States, the Psoriasis Association in the United Kingdom and Psoriasis Australia offer advocacy and education about psoriasis in their respective countries. Pharmacy costs are the main source of direct expense, with biologic therapy the most prevalent. These costs increase significantly when co-morbid conditions such as heart disease, hypertension, diabetes, lung disease and About Psoriasis Beschreibung Ausschläge Aqua disorders are factored Psoriasis besiegt. The role of insulin resistance in the pathogenesis of psoriasis is currently under investigation.
Preliminary research has suggested that antioxidants such as polyphenols may have beneficial effects on the inflammation characteristic of psoriasis. From Wikipedia, the free encyclopedia. List of human leukocyte antigen alleles associated with cutaneous conditions. Overview of psoriasis and guidelines of care for the treatment of Psoriasis besiegt with biologics". J Am Acad Dermatol. Retrieved 22 April National Institute of Arthritis and Musculoskeletal and Skin Diseases.
Retrieved 1 July Identification and Management of Psoriasis and Associated ComorbidiTy IMPACT project team. Drug Des Devel Ther. Retrieved 16 March Clinical Dermatology 10th ed. From the Medical Board of the National Psoriasis Foundation". Am J Psoriasis besiegt Dermatol. Greenberg, Michael Glick, Psoriasis besiegt A. N Engl J Med. Retrieved 8 Haferflocken Bäder in Psoriasis The American Journal of Human Genetics.
J Eur Psoriasis besiegt Dermatol Venereol. J Int AIDS Soc. A Review of T-cell Subsets and Cytokine Profiles". Psoriasis besiegt Cutan Med Surg. Expert Rev Gastroenterol Hepatol. Clinical dermatology 4th ed.
Cytokine Growth Factor Rev. Br J Community Nurs. Skin Disease, Immune Response and Cytokines. Clin Rev Allerg Immunol. The International League Psoriasis besiegt Dermatological Societies.
Archived from the original on J Am Board Fam Med. Clin Cosmet Investig Psoriasis besiegt. Br J Clin Dermatol. Arthritis Care Res Hoboken.
Cochrane Database Psoriasis besiegt Rev. Guidelines of care for the management and treatment of psoriasis with topical therapies". The Cochrane database of systematic reviews. International Journal of Dermatology. Indian J Dermatol Venereol Leprol. Psoriasis American Academy of Dermatology". A Review of Psoriasis besiegt III Trials.
The Point of View of the Nutritionist. Int J Environ Res Public Health Review. Clin Cosmet Investig Dermatol Review. Nat Rev Gastroenterol Hepatol Review. Health Qual Life Outcomes. Clinical dermatology a color guide to diagnosis and therapy 5th ed. Am J Med Sci. Ir J Med Psoriasis besiegt Psoriatic and Reactive Arthritis: A Companion to Rheumatology 1st ed. The American Journal of Managed Care. L40 ICD - 9-CM: Diseases of the skin and appendages by morphology.
Freckles lentigo melasma nevus melanoma. Aphthous stomatitis oral candidiasis lichen planus leukoplakia pemphigus vulgaris mucous membrane pemphigoid cicatricial pemphigoid herpesvirus coxsackievirus syphilis systemic histoplasmosis squamous-cell carcinoma. Papulosquamous disorders L40—L45— Guttate psoriasis Psoriatic arthritis Psoriatic erythroderma Drug-induced psoriasis Inverse psoriasis Napkin psoriasis Seborrheic-like psoriasis.
Pityriasis lichenoides Pityriasis lichenoides et varioliformis Psoriasis besiegtPityriasis lichenoides chronica Lymphomatoid papulosis Small plaque parapsoriasis Digitate dermatosisXanthoerythrodermia perstans Large plaque parapsoriasis Retiform parapsoriasis. Pityriasis rosea Pityriasis rubra pilaris Pityriasis rotunda Pityriasis amiantacea.
Hepatitis-associated lichen planus Lichen planus pemphigoides. Lichen nitidus Lichen striatus Lichen ruber moniliformis Gianotti—Crosti syndrome Erythema dyschromicum perstans Idiopathic eruptive macular pigmentation Keratosis lichenoides chronica Kraurosis vulvae Lichen sclerosus Lichenoid dermatitis Lichenoid reaction Psoriasis besiegt graft-versus-host disease.
Retrieved from " https: Autoimmune diseases Cutaneous conditions Psoriasis. Uses editors parameter CS1 maint: Uses authors parameter Good articles Articles with contributors Psoriasis besiegt Articles with DMOZ links Wikipedia articles with LCCN identifiers RTT.
Navigation menu Personal tools Not logged in Talk Contributions Create account Log in. Views Read Edit View history. Navigation Main page Contents Featured content Current events Random article Donate to Wikipedia Wikipedia store. Interaction Help About Wikipedia Community portal Recent changes Contact page.
Genetic disease triggered by environmental factors . Based on symptoms . Steroid creamsvitamin D3 cream, ultraviolet lightimmune system suppressing medications such as methotrexate .
Pustulosis palmaris et plantaris. Wikimedia Commons has media related to Psoriasis. Epidermal wart callus seborrheic keratosis acrochordon molluscum contagiosum actinic keratosis squamous-cell carcinoma basal-cell carcinoma Merkel-cell carcinoma nevus sebaceous trichoepithelioma. Red Blanchable Erythema Generalized drug eruptions viral exanthems toxic erythema systemic lupus Psoriasis besiegt. Lichen planus configuration Annular Linear morphology Hypertrophic Atrophic Bullous Ulcerative Actinic Pigmented site Mucosal Nails Peno-ginival Vulvovaginal overlap synromes with lichen sclerosus with lupus erythematosis other:
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